Carbonyl stress and a combination of astaxanthin/vitamin C induce biochemical changes in human neutrophils

► Effect of methylglyoxal/high glucose on neutrophils functional parameters. ► Also, if the addition of astaxanthin with vitamin C modulates those parameters. ► Methylglyoxal/high glucose promote an injury to the function of neutrophils. ► Astaxanthin with vitamin C proved to be a powerful antioxidant in human neutrophils. ► Association of astaxanthin/vitamin C improved neutrophil function and redox status.