Short-term physical activity intervention decreases femoral bone marrow adipose tissue in young children: A pilot study

► Early physical activity interventions may present a timely opportunity in which bone's sensitivity to mechanical signals can be harnessed. ► Attenuation of femoral bone marrow adipose tissue accrual may be relevant for long-term bone quality optimization. ► Femoral bone marrow adipose tissue was significantly decreased in children participating in intervention; significant change not observed in control-group. ► Bone mineral content was not statistically different following a 10-week physical activity intervention.