کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5913044 | 1161856 | 2014 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
mRNA transport meets membrane traffic
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: mRNA transport meets membrane traffic mRNA transport meets membrane traffic](/preview/png/5913044.png)
چکیده انگلیسی
Active transport and local translation of mRNAs ensure the appropriate spatial organization of proteins within cells. Recent work has shown that this process is intricately connected to membrane trafficking. Here, we focus on new findings obtained in fungal model systems. Important highlights are that RNA-binding proteins recognize cargo mRNA synergistically and that mRNAs are co-transported with membranous compartments such as the endoplasmic reticulum (ER) and endosomes. We further discuss a novel concept of endosome-coupled translation that loads shuttling endosomes with septin cargo, a process important for correct septin filamentation. Interestingly, evidence is accumulating that RNA and membrane trafficking are also tightly interwoven in higher eukaryotes, suggesting that this phenomenon is a common theme and not an exception restricted to fungi.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Trends in Genetics - Volume 30, Issue 9, September 2014, Pages 408-417
Journal: Trends in Genetics - Volume 30, Issue 9, September 2014, Pages 408-417
نویسندگان
Ralf-Peter Jansen, Dierk Niessing, Sebastian Baumann, Michael Feldbrügge,