کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
596256 1454036 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fabrication of fluorescent microparticles by doping water-soluble CdTe nanocrystals into calcium carbonate for monitoring intracellular uptake
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Fabrication of fluorescent microparticles by doping water-soluble CdTe nanocrystals into calcium carbonate for monitoring intracellular uptake
چکیده انگلیسی

3-Mercaptopropyl acid (MPA) capped CdTe quantum dots (QDs) were embedded into CaCO3 microparticles with a size of 1.4–4.4 μm by addition of the QDs into Ca(NO3)2 solution during a mineralization process. Compared to the parent QDs, about 1/7–1/3 photoluminescence efficiency of the embedded QDs was preserved, enabling the CaCO3(CdTe) particles visible under UV irradiation. The structure and morphology of the CaCO3(CdTe) particles were characterized by X-ray diffraction (XRD), UV–vis spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and confocal laser scanning microscopy (CLSM). Protected by the CaCO3 particles, the QDs in the composites were more stable against long term storage, UV irradiation and cell culture medium containing serum. The CaCO3(CdTe) particles could be internalized into live cells, human liver cancer cells (HepG2), for example, and most of which distributed in the lysosomes as revealed by confocal microscopy. Also the CaCO3(CdTe) particles had low cytotoxicity in comparison with the parent CdTe QDs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Volume 336, Issues 1–3, 20 March 2009, Pages 115–122
نویسندگان
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