کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6117247 1217176 2014 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Autoimmunity: Break-through in the diagnosis and treatment of immune-mediated inflammatory diseases
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Autoimmunity: Break-through in the diagnosis and treatment of immune-mediated inflammatory diseases
چکیده انگلیسی
The study of fundamental mechanisms of autoimmunity has been instrumental to clinical progress in the diagnosis and treatment of a range of immune-mediated inflammatory disorders. Dutch immunology has made major contributions to these developments, ranging from fundamental studies on immune cells, antibodies and cytokines to translational and clinical studies with targeted therapies in patients. In this paper we illustrate the progress made in our understanding of autoimmunity and the translational implications for human disease management by focusing on three areas: the autoantibody response in rheumatoid arthritis (RA), T-B cell interactions in Sjögren's syndrome (SS), and cytokine targeting in spondylarthritis (SpA).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunology Letters - Volume 162, Issue 2, Part B, December 2014, Pages 150-162
نویسندگان
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