کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6135662 1224884 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
High leptospiremia is associated with low gamma-delta T cell counts
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
High leptospiremia is associated with low gamma-delta T cell counts
چکیده انگلیسی
The role of innate immune cells either to mount appropriate defense mechanisms or to drive uncontrolled tissue injuries during acute leptospirosis is poorly understood. This study aimed at characterizing the selective mobilization of innate immune cells and the level of target organ injuries in response to leptospiremia. We focused on gamma-delta (γ-δ) T cells. Patients were prospectively assessed for cell count by cytometry, for bacterial load by PCR in plasma samples and for levels of soluble acute phase tissue enzymes. We found that the level of γ-δ T cells was low and inversely correlated to liver injuries and leptospiremia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microbes and Infection - Volume 17, Issue 6, June 2015, Pages 451-455
نویسندگان
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