کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6314269 | 1619069 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Prenatal exposure to environmental contaminants and behavioural problems at age 7-8Â years
ترجمه فارسی عنوان
قرار گرفتن در معرض آلاینده های محیطی و مشکلات رفتاری در سن 7-8 سالگی قبل از زایمان؟
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کلمات کلیدی
AHRHR-ICP-MSFLEHSdichlorodiphenyltrichloroethaneSDQLOQHCBIQRPCBGC-MS - کروماتوگرافی گازی-طیف سنج جرمیp,p′-DDE - p، p'-DDEHexachlorobenzene - بنزن هگزاکلراید، هگزاکلروبنزنADHD - بیشفعالیPolychlorinated biphenyls - بیفنیل پلیکلر Dioxin-like compounds - ترکیبات دیوکسین مانندLOD یا Limit of detection - حد تشخیصDDT - دیکرو دیفنیل تری کلرواتانChild behaviour - رفتار کودکbody mass index - شاخص توده بدنBMI - شاخص توده بدنیHeavy metals - فلزات سنگینinterquartile range - محدوده بین محدبlimit of quantification - محدودیت اندازه گیریlimit of detection - محدودیت تشخیصodds ratio - نسبت شانس هاStrengths and Difficulties Questionnaire - پرسشنامه های قدرت و دشواریCadmium - کادمیمAttention deficit/hyperactivity disorder - کمبود توجه / اختلال بیش فعالیaryl hydrocarbon receptor - گیرنده آرویل هیدروکربن
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
چکیده انگلیسی
Animal studies showed that the developing brain is particularly sensitive to chemical exposure. Human studies carried out in areas with high exposures have proven neurodevelopmental disorders in relation to e.g. lead and PCBs. Whether these chemicals are associated with behavioural problems in childhood at current environmental levels is not well known. Therefore, we assessed the association between prenatal exposure to lead, cadmium, PCBs, dioxin-like compounds, HCB and p,pâ²-DDE and behavioural problems in 7-8Â year old children. Prenatal exposure data were obtained from the Flemish mother-new-born cohort. Lead, cadmium, PCBs, dioxin-like compounds, HCB and p,pâ²-DDE were analysed in cord blood. When the child reached 7-8Â years, 270 mothers completed the Strengths and Difficulties Questionnaire assessing their children's behavioural health. We found that doubling the prenatal lead exposure (cord blood lead levels) was associated with a 3.43 times higher risk for hyperactivity in both boys and girls. In addition, total difficulties were 5.08 times more likely in the highest tertile for prenatal lead exposure compared to the lowest tertile. In girls, total difficulties were 4.92 more likely when doubling cord blood p,pâ²-DDE, whereas no significant association was found in boys. Further, we noted in boys a 1.53 times higher risk for emotional problems when doubling cord blood cadmium, whereas no significant association was found in girls. These results indicate that the presence of environmental contaminants influences the mental health of the next generation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environment International - Volume 59, September 2013, Pages 225-231
Journal: Environment International - Volume 59, September 2013, Pages 225-231
نویسندگان
Isabelle Sioen, Elly Den Hond, Vera Nelen, Els Van de Mieroop, Kim Croes, Nik Van Larebeke, Tim S. Nawrot, Greet Schoeters,