کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6486778 | 1222 | 2012 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Prospects of nanoparticle-DNA binding and its implications in medical biotechnology
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کلمات کلیدی
SERSss-DNAPeptide nucleic acids (PNA)BuckminsterfullereneSWCNTsCNPC60PNAMWCNTsAFMSingle-stranded DNA - DNA تک رشته ایdouble-stranded DNA - DNA رشته ایds-DNA - Ds-DNADNA binding - اتصال DNATem - این استCho - برایChinese Hamster Ovary - تخمدان هامستر چینیSPR - تشدید پلاسمون سطحیSurface plasmon resonance - تشدید پلاسمون سطحیMolecular interactions - تعاملات مولکولیDNA structure - ساختار DNASurface enhanced Raman spectroscopy - سطح افزایش طیف سنجی رامانCytotoxity - سیتوتاکسیتTransmission electron microscopy - میکروسکوپ الکترونی عبوریatomic force microscopy - میکروسکوپ نیروی اتمیNanoparticles - نانوذراتGold nanoparticles - نانوذرات طلاSilver nanoparticles - نانوذرات نقرهCarbon nanoparticles - نانوذرات کربنیSingle-walled Carbon Nanotubes - نانولوله های کربنی تک دیوارهMulti-walled carbon nanotubes - نانولوله های کربنی چند دیوارهpolymerase chain reaction - واکنش زنجیره ای پلیمرازPCR - واکنش زنجیرهٔ پلیمرازSingle nucleotide polymorphism - پلیمورفیسم تک نوکلئوتیدیSNP - چندریختی تک-نوکلئوتید
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Bio-nanotechnology is a new interdisciplinary R&D area that integrates engineering and physical science with biology through the development of multifunctional devices and systems, focusing biology inspired processes or their applications, in particular in medical biotechnology. DNA based nanotechnology, in many ways, has been one of the most intensively studied fields in recent years that involves the use and the creation of bio-inspired materials and their technologies for highly selective biosensing, nanoarchitecture engineering and nanoelectronics. Increasing researches have been offered to a fundamental understanding how the interactions between the nanoparticles and DNA molecules could alter DNA molecular structure and its biochemical activities. This minor review describes the mechanisms of the nanoparticle-DNA binding and molecular interactions. We present recent discoveries and research progresses how the nanoparticle-DNA binding could vary DNA molecular structure, DNA detection, and gene therapy. We report a few case studies associated with the application of the nanoparticle-DNA binding devices in medical detection and biotechnology. The potential impacts of the nanoparticles via DNA binding on toxicity of the microorganisms are briefly discussed. The nanoparticle-DNA interactions and their impact on molecular and microbial functionalities have only drown attention in recent a few years. The information presented in this review can provide useful references for further studies on biomedical science and technology.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biotechnology Advances - Volume 30, Issue 6, NovemberâDecember 2012, Pages 1721-1732
Journal: Biotechnology Advances - Volume 30, Issue 6, NovemberâDecember 2012, Pages 1721-1732
نویسندگان
Hongjie An, Bo Jin,