کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6492135 | 43469 | 2012 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Use of a mixture of glucose and methanol as substrates for the production of recombinant trypsinogen in continuous cultures with Pichia pastoris Mut+
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Use of a mixture of glucose and methanol as substrates for the production of recombinant trypsinogen in continuous cultures with Pichia pastoris Mut+ Use of a mixture of glucose and methanol as substrates for the production of recombinant trypsinogen in continuous cultures with Pichia pastoris Mut+](/preview/png/6492135.png)
چکیده انگلیسی
⺠Glucose is a feasible partial substitute for methanol in recombinant protein production with Pichia pastoris Mut+ strains. ⺠The repressive effect of glucose on methanol utilization was eliminated in carbon/energy limited continuous cultures. ⺠With mixtures of glucose and methanol both yield of biomass per consumed substrate and productivity were enhanced. ⺠Production of porcine trypsinogen was only stable at low dilution rates.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biotechnology - Volume 157, Issue 1, January 2012, Pages 180-188
Journal: Journal of Biotechnology - Volume 157, Issue 1, January 2012, Pages 180-188
نویسندگان
Leona Paulová, Petr Hyka, Barbora Branská, Karel Melzoch, Karin Kovar,