کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6493279 1418050 2018 32 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biogenic synthesis, characterization of gold and silver nanoparticles from Coleus forskohlii and their clinical importance
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Biogenic synthesis, characterization of gold and silver nanoparticles from Coleus forskohlii and their clinical importance
چکیده انگلیسی
In modern era, the great interest and demand among chemists and researchers for metal nanoparticles is increasing in the application of biomedical fields, textiles, cosmetics and various sectors. Consequently, the present study reports an eco-friendly, cost-effective, rapid and easy method to produce environment-friendly metal nanoparticles to prevent exhaustion of metal resources. In this context, gold and silver metal nanoparticles were green synthesized using the Root Extract of Coleous forskohlii (RECo) as capping and reducing agent. The synthesized gold (GNPs) and silver nanoparticles (SNPs) were characterized using UV-Visible spectrophotometer, High-resolution transmission electron microscopy (HR-TEM), Particle size analysis (PSA), Fourier-transform infrared spectroscopy (FT-IR) and X-Ray Diffractometer (XRD). Their clinical importance was analysed using anti-oxidant assay (DPPH - 2,2-diphenyl-1-picrylhydrazyl and Phosphomolybdenum PMA) and cytotoxicity (MTT assay) against HEPG2 (liver cancer cell lines). Further, the antimicrobial activity against two microorganisms were tested using disc diffusion method against Proteus vulgaris pathogen and Micrococcus luteus pathogen. RECo-GNPs and SNPs were found to be stable in aqueous medium for a longer time and exhibited favorable anti-oxidant, anti-bacterial and anti-cancer activity. The phytoconstituents present in the root extract of Coleous forskohlii was elucidated using GC-MS analysis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 183, June 2018, Pages 251-257
نویسندگان
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