کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6603236 | 1424086 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A sensitive ratiometric electrochemiluminescence biosensor for hypoxanthine detection by in situ generation and consumption of coreactants
ترجمه فارسی عنوان
حسگر سنجش حساسیت سنجی الکتروشیمیومیومسنسنت حساسیت به تشخیص هیپوکسانتین با تولید و مصرف هسته آفتاب
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
چکیده انگلیسی
In this work, a ratiometric electrochemiluminescence (ECL) biosensor was constructed for testing hypoxanthine (Hx). The reduced graphene oxide-CdTe quantum dots (rGO-CdTe QDs) and luminol were chose as the cathodic and anodic probes, the reactant (dissolved O2) and the product (H2O2) in enzymatic reaction served as their coreactants, respectively. The enzymatic reaction triggered an opposite changes in the concentration of the reactant and the product, thus resulting in a reverse change trend in two ECL signals. The logarithmic value of two ECL signals intensity ratio showed a good linear relationship with the logarithmic value of the concentration of Hx from 0.020â¯nM to 2.0â¯Î¼M. The limit of detection was 0.007â¯nM. Such a construction strategy decreased the interference from environment and improved the detection accuracy of Hx. The integration of CdTe QDs and luminol provides more choice for constructing ratiometric ECL biosensors, especially for oxidase-based ECL sensing system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 271, 1 May 2018, Pages 173-179
Journal: Electrochimica Acta - Volume 271, 1 May 2018, Pages 173-179
نویسندگان
Fumei Zuo, Han Zhang, Ji Xie, Shihong Chen, Ruo Yuan,