Ultrasensitive determination of microribonucleic acids in cancer cells with nanostructured-disposable electrodes using the viral protein p19 for recognition of ribonucleic acid/microribonucleic acid homoduplexes

Disposable biosensors for simple, rapid and sensitive determination of miRNAs in cancer cells based on their direct hybridization and efficient labeling of the RNA/miRNA homoduplexes formed with viral protein p19 and an HRP-labeled antibody at SH-RNA/MCH-AuNP-SPCEs.244