Silicaethylphosphatrioxaadamantane—A new support for palladium catalysts and evaluation in Suzuki coupling reactions

New highly active heterogeneous silicaethylphosphatrioxaadamantane palladium catalysts with very low millimole per gram palladium load are reported. Applied to a broad range of Suzuki substrate pairs in 0.1–0.2 mol%, these catalysts are very effective, reusable and resistant to leaching for reactions in hot xylene or with microwave irradiation of EtOH:H2O:DME solutions.

We report on the immobilisation of the phosphaadamantane function onto silica via an ethyl linker group and the development of heterogeneous catalysts for use in Pd-catalysed Suzuki couplings.Figure optionsDownload as PowerPoint slide