کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
69438 48766 2016 4 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Urease-catalyzed synthesis of aminocyanopyridines from urea under fully green conditions
ترجمه فارسی عنوان
سنتز aminocyanopyridines از اوره با کاتالیز اوره تحت شرایط کاملا سبز
کلمات کلیدی
اوره؛ واکنش های آنزیمی؛ تولید درچای آمونیاک؛ زیست سازگار؛ پیریدین ها
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
چکیده انگلیسی


• This work supports the catalytic performance of urease in organic synthesis.
• This specific urease-catalyzed reaction inhibits by trace amount of Pb2+, Hg2+, or Ag+.
• The authority of urease is bio-production of ammonia from urea.

This is an original work on catalytic performance of urease in organic synthesis which in one-pot dissociation of urea and condensation of the in situ generated ammonia with aldehydes, acetophenones, and malononitrile occurs in water to give 2-amino-3-cyanopyridines. Comparative experiments with ammonium salts supported the enzymatic specify of 0.01 g/mL (50 U/mg) of urease for bio-production of ammonia, while trace amount of heavy metal ions such as Pb2+, Hg2+, and Ag+ inhibit these specific reactions. The scalability and promiscuity of urease facilitate the applicability of the process for biotechnological organic reactions based on ammonia.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Catalysis B: Enzymatic - Volume 127, May 2016, Pages 89–92
نویسندگان
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