The production of 1,3-propanediol from mixtures of glycerol and glucose by a Klebsiella pneumoniae mutant deficient in carbon catabolite repression

► We prepared a crr mutant strain of Klebsiella pneumonia mutant, in which carbon catabolite repression (CCR) was abolished. ► Production of 1,3-propanediol from glycerol upon fermentation of the crr mutant increased by the presence of glucose. ► This is the first report to show that elimination of CCR in K. pneumoniae strains used for 1,3-PD biosynthesis.