A novel pathway construction in Candida tropicalis for direct xylitol conversion from corncob xylan

- A new β-xylanase gene was discovered from Aspergillus terreus.
- The co-expression plasmid of xylanase and xylosidase was constructed.
- A novel xylan transforming pathway was integrated in Candida tropicalis BIT-Xol-1.
- Xylanase and xylosidase were secretively expressed in the engineered C. tropicalis.
- It simultaneously saccharify and transform xylan to xylitol efficiently.