کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
71037 48863 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Production of glycidyl ethers by chemo-enzymatic epoxidation of allyl ethers
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
پیش نمایش صفحه اول مقاله
Production of glycidyl ethers by chemo-enzymatic epoxidation of allyl ethers
چکیده انگلیسی

Production of glycidyl ethers is industrially carried out by reacting alcohols with epichlorhydrin, a potentially carcinogenic compound. This paper investigates a less hazardous alternative—that of a chemo-enzymatic process in which Candida antarctica lipase B catalysed generation of peracid from a carboxylic acid is followed by a Prileshajev epoxidation of the corresponding allyl ether. Trimethylolpropane monoallyl ether (TMPME) was used as a model substrate. A maximal epoxide product yield of 77% was achieved through the optimization of temperature, acid concentration and hydrogen peroxide concentration. Peracid formation was considerably faster than the subsequent epoxidation step, and accumulation of the peracid was found to be important to drive the epoxidation forward.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Catalysis B: Enzymatic - Volume 54, Issues 1–2, July 2008, Pages 1–6
نویسندگان
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