High selective and sensitive capillary electrophoresis-based electrochemical immunoassay enhanced by gold nanoparticles

► AuNPs were added to buffer solution to enhance CE based electrochemical immunoassay. ► AuNPs improved separation resolution by modifying the analytes mobilities. ► AuNPs were used as multianalyte carriers to achieve an amplification of EC signal. ► The four shellfish toxins were baseline separated by using of AuNPs.