کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7238619 1471144 2018 35 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
pH-triggered surface charge-reversal nanoparticles alleviate experimental murine colitis via selective accumulation in inflamed colon regions
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
pH-triggered surface charge-reversal nanoparticles alleviate experimental murine colitis via selective accumulation in inflamed colon regions
چکیده انگلیسی
In this study, we developed, through intelligent design, pH-triggered surface charge-reversal lipid nanoparticles, which were shown to precisely deliver a corticosteroid drug to inflamed colon segments in an ulcerative colitis mouse model. The results of the study suggest that the pH-triggered charge-reversal lipid nanoparticles are a promising drug nanocarrier for colon-targeted therapy, including ulcerative colitis treatments.190
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 14, Issue 3, April 2018, Pages 823-834
نویسندگان
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