کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7601633 1492155 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The nutritional supplement Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-κB/MAPK activation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
The nutritional supplement Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-κB/MAPK activation
چکیده انگلیسی
► Active Hexose Correlated Compound (AHCC) is used to boost the immune function. ► AHCC induced the production of GROα and MCP1 in IEC18 cells and of IL8 in HT29 cells. ► AHCC induced IL1β, IL6 and TNFα production in human monocytes (THP-1 cells). ► The stimulatory response was evoked by TLR4/MyD88, MAPK and NF-κB dependent pathways. ► AHCC may work in part by enhancing mucosal barrier function and defence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 136, Issues 3–4, 1–15 February 2013, Pages 1288-1295
نویسندگان
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