کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7622414 | 1494525 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Production of the bioactive isoflavone O-desmethylangolensin by Enterococcus faecium INIA P553 with high efficiency
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Healthy effect of isoflavones consumption is attributed to their bioactive metabolites such as O-desmethylangolensin (O-DMA) produced by intestinal bacteria. Evidence from in vitro studies suggests that O-DMA has several cancer-related biological actions. Enterococcus spp. are indigenous species of the human gastrointestinal tract. Significant attention has been focused on Enterococcus faecium strains with probiotic and /or technological interest in foods. In this work, we describe the production of the bioactive isoflavones O-DMA and 6-hydroxy O-DMA by the strain E. faecium INIA P553. O-DMA was produced from dihydrodaidzein, daidzein, daidzin and formononetin, and 6-hydroxy O-DMA from dihydrogenistein, genistein and genistin with high efficiency. To our knowledge, it is the first bacterium with probiotic potential capable of producing O-DMA and 6-hydroxy O-DMA. Therefore, this strain shows potential applications in biotechnology in functional foods and as probiotic.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 40, January 2018, Pages 180-186
Journal: Journal of Functional Foods - Volume 40, January 2018, Pages 180-186
نویسندگان
Pilar Gaya, Ángela Peirotén, Inmaculada Álvarez, Margarita Medina, José Mª. Landete,