کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7626492 | 1494579 | 2018 | 34 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization by liquid chromatography-mass spectrometry and antioxidant activity of an ethanolic extract of Inula viscosa leaves
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
Inula viscosa (I. viscosa) is a common Mediterranean plant, well known for its content on bioactive molecules. The chemical composition of an ethanolic extract from I. viscosa leaves, growing in Algeria, was analysed by liquid chromatography coupled to photodiode array detection and electrospray ionization mass spectrometry (LC-DAD-ESI-MS/MS) operating in negative and positive mode. The methodology used revealed the presence of 51 compounds from which 47 were putatively identified, including 11 phenolic acids, 23flavonoids, one lignan and 12 terpenoids. Twenty-six of these compounds are described for the first time in I. viscosa. Antioxidant activity was measured using three different and complementary chemical assays: DPPH radical scavenging activity, oxygen radical absorbance capacity (ORAC) and hydroxyl radical scavenging capacity (HOSC). Results demonstrate that ethanolic leaf extract exhibit a high scavenging ability against DPPH (157.72â¯Â±â¯6.45â¯Î¼M TE/g DW), peroxyl (4471.42â¯Â±â¯113.16â¯Î¼M TE/g DW) and hydroxyl (630.10â¯Â±â¯17.81â¯Î¼M TE/g DW) radicals, indicating that I. viscosa can be a promising source of bioactive compounds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 156, 15 July 2018, Pages 297-306
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 156, 15 July 2018, Pages 297-306
نویسندگان
Naoual Kheyar-Kraouche, Andreia Bento da Silva, Ana Teresa Serra, Fatiha Bedjou, Maria R. Bronze,