کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7630771 1494635 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
An activity-integrated strategy involving ultra-high-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and fraction collector for rapid screening and characterization of the α-glucosidase inhibitors in Coptis chinensis Franch.
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
An activity-integrated strategy involving ultra-high-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and fraction collector for rapid screening and characterization of the α-glucosidase inhibitors in Coptis chinensis Franch.
چکیده انگلیسی

- An activity integrated strategy was developed to screen inhibitors of α-glucosidase.
- Alkaloids were the main inhibitors of α-glucosidase in huanglian extract.
- Coptisine, epiberberine, jatrorrhizin and berberine were α-glucosidase inhibitors.
- A powerful tool for screening and identifying active ingredients from TCMs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 100, November 2014, Pages 79-87
نویسندگان
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