A novel strategy to evaluate the quality of traditional Chinese medicine based on the correlation analysis of chemical fingerprint and biological effect

The bubble chart indicated that chemical fingerprints of Rehmanniae glutinosa (RG) from different origins had a significant difference. The larger the diameter of the bubble, the worse the therapeutic effects of RG treating kidney yin deficiency. Efficacy-related components could be used to evaluate the quality and predict therapeutic effects of RG. PH: processed RG samples from Henan province. PS: processed RG samples from Shanxi province. RH: raw RG samples from Henan province. RS: raw RG samples from Shanxi province. PS4: processed RG sample from Shanxi province, used for the quality verification test as a new RG sample.