Preparation and adsorption of bovine serum albumin-imprinted polyacrylamide hydrogel membrane grafted on non-woven polypropylene

The figure shows that the imprinting efficiency of PP-g-PAM MIPs gradually decreased with the cycle times (from 3.30 to 2.56) and reached a stable value after three cycle times. The imprinting efficiency of PP-g-PAM MIPs was maintained at 76% of the initial value even after five cycles. However, the imprinting efficiency of BSA-imprinted PAM microspheres continually declined with increasing cycle times. After five cycle times, the imprinting effect almost disappeared. This result is probably due to the soft texture of gel microspheres, which cannot stabilize the shape of the binding sites. By contrast, the strength of PP-g-PAM MIPs was significantly improved and the shape of the binding sites was almost stabilized.