Improved sample treatment for the determination of bisphenol A and its chlorinated derivatives in sewage sludge samples by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry

► Method to identify and quantify BPA and chlorinated derivatives in sewage sludge. ► A pressurized liquid extraction procedure is optimized prior to LC-MS/MS analysis. ► Solid phase extraction (SPE) is not necessary to improve the results of the analysis. ► Validation of the method: quality parameters, accuracy (trueness and precision). ► Samples from a conventional activated sludge and from a membrane bioreactor (MBR) plants.