Ultra trace determination of bromate in mineral water and table salt by liquid chromatography-tandem mass spectrometry

► This method is directly used to determine bromate by LC-MS/MS after derivatization. ► Selection of reagent and its amount, reaction temp. and time and pH were optimized. ► Best reagent is 2,6-DMA. ► LOD and LOQ in table salt were 0.07 and 0.23 μg/kg respectively and RSD was less than 9.0%.