Automated in-syringe dispersive liquid-liquid microextraction

In this work, we describe and review recent applications of a novel approach to perform fully-automated in-syringe DLLME based on the use of computer-controlled bi-directional syringe pumps. The in-syringe-DLLME technique enables precise flow control over the extractant and the concomitant detection of the analytes “in-syringe”, within a peripheral flow network, or by introduction into coupled detectors.