کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7792897 | 1500657 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Polysaccharides with immunomodulating properties from the bark of Parkia biglobosa
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
LPSrhamnogalacturonan type Iarabinogalactan type IAG-IMacrophage stimulationParkia biglobosaRG-IIRG-IXylRHAGlcAarabinogalactan type IIAG-IIGlcArabinoseGC–MS - GC-MSGalacturonic acid - اسید گالاکاتورونیکGlucuronic acid - اسید گلوکورونیکImmunomodulation - تنظیم ایمنی ARA - در حال حاضرComplement system - دستگاه کمپلمان، سیستم کمپلمانrhamnose - رامنوزgas chromatography–mass spectrometry - طیف سنجی جرم کروماتوگرافی گازlipopolysaccharide - لیپوپلی ساکاریدMannose - مانوزMan - مردNitric oxide - نیتریک اکسیدPectic polysaccharides - پلی ساکارید پکتGal - گالGalA - گالاGalactose - گالاکتوزمی Xylose - گزیلوزGlucose - گلوکز
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The bark of Parkia biglobosa is used in traditional medicine to cure a wide range of illnesses. Polysaccharides were extracted from the bark with 50% ethanol-water, 50 °C and 100 °C water, and seven active fractions obtained by anion exchange chromatography and gel filtration. The complement fixation and macrophage stimulating activities of the different fractions were determined. The acidic fractions PBEII-I and PBEII-IV were the most active in the complement fixation assay, but the other fractions were also potent compared to the positive control BPII from Biophytum petersianum. Fractions PBEII-I and PBEII-IV were also the most potent fractions in stimulating macrophages to release nitric oxide. Structural studies showed that PBEII-I and PBEII-IV were pectic type polysaccharides, containing arabinogalactan type II structures. The observed differences in biological activities among the seven purified polysaccharide sub-fractions are probably due to differences in monosaccharide compositions, linkage types and molecular sizes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 101, 30 January 2014, Pages 457-463
Journal: Carbohydrate Polymers - Volume 101, 30 January 2014, Pages 457-463
نویسندگان
Yuan-Feng Zou, Bing-Zhao Zhang, Kari Tvete Inngjerdingen, Hilde Barsett, Drissa Diallo, Terje Einar Michaelsen, Elnour El-zoubair, Berit Smestad Paulsen,