Surfactant-free biodegradable polymeric nanoparticles generated from self-organized precipitation route: Cellular uptake and cytotoxicity

- We apply SORP route to produce uniform surfactant-free biodegradable polymeric NPs.
- Size and size distribution of NPs can be tuned by varying experiment conditions.
- Functional species can be encapsulated to produce multifunctional NPs.
- In vitro cellular uptake and cytotoxicity of different NPs are conducted.
- Possible mechanism of cytotoxicity of the NPs is also investigated.