Polyoxometalate coordination induced controllable release of quinolone in hybrid film

The vanadium-quinolone functionalized polymolybdates of (NH4)2[(γ-Mo8O26){VO(CF)2}2] (1) and (NH4)2[(γ-Mo8O26){VO(NF)2}2] (2) (CF = ciprofloxacin; NF = norfloxacin) are firstly demonstrated. When complex 1 or 2 is transferred into PVA film, it shows lower release rate in solution than that of CF- or NF-PVA film, it opens a new way to realize the controllable release of antibacterial drugs at molecular level.283