In vitro DNA binding studies of lenalidomide using spectroscopic in combination with molecular docking techniques

In this work, the binding interaction between the drug lenalidomide (LEN) and calf thymus DNA (ct-DNA) was studied by using fluorescence spectroscopy, ultraviolet-visible (UV-vis), circular dichroism (CD) under imitated physiological pH value (pH = 7.4) coupled with molecular docking.222