Influence of cellular arachidonic acid levels on phospholipid remodeling and CoA-independent transacylase activity in human monocytes and U937 cells

► Phospholipid arachidonate remodeling in U937 cells is faster than in human monocytes. ► Arachidonate remodeling does not depend on the differentiation stage of the cells. ► The intracellular content of arachidonate determines the rate of remodeling. ► Arachidonate‐loaded U937 cells exhibit a reduced CoA-transacylase activity.