Increased clopidogrel response is associated with ABCC3 expression: A pilot study

► Treatment with clopidogrel can prevent recurrent ischaemic events. ► Clopidorel response was associated with risk for recurrent cardiovascular events. ► ABCB1 and ABCC3 can limit intestinal absorption. ► Low ABCC3 expression had higher probability to have a good response to clopidogrel. ► ABCC3 mRNA expression can be contributed with increase responses to clopidogrel.