In vitro and in vivo efficacy of partially purified herbal extracts against bacterial fish pathogens

The success of any fish culture depends on the health status of cultivated species. Fish diseases are one of major threats in aquaculture industry inflicting heavy mortality in the world. To prevent and control of the diseases traditionally was used several antibiotics or chemicals during the last few decades. However, these methods have been criticized for their negative impacts such as accumulation of drugs in tissues, development of drug resistance, and immunosuppression. Several herbal and their active principles possess better antioxidant activity, phenols content, reducing power, and free radical scavenging activity. Therefore in the present study was isolated new fish pathogen from the infected fish and to investigated antioxidant activity and their pathogenicity and hematological changes in dotty back, P. dilectus against P. mirabilis. This work is novel in aquaculture to design or prepare cost effective drug or feed for fishes.