کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8736167 1591112 2016 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A review on emerging frontiers of house dust mite and cockroach allergy research
ترجمه فارسی عنوان
بررسی مرزهای در حال ظهور تحقیقات آلرژی جوجه های گوشتی و سوسک
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
چکیده انگلیسی
Currently, mankind is afflicted with diversified health issues, allergies being a common, yet little understood malady. Allergies, the outcome of a baffled immune system encompasses myriad allergens and causes an array of health consequences, ranging from transient to recurrent and mild to fatal. Indoor allergy is a serious hypersensitivity in genetically-predisposed people, triggered by ingestion, inhalation or mere contact of allergens, of which mite and cockroaches are one of the most-represented constituents. Arduous to eliminate, these aeroallergens pose constant health challenges, mostly manifested as respiratory and dermatological inflammations, leading to further aggravations if unrestrained. Recent times have seen an unprecedented endeavour to understand the conformation of these allergens, their immune manipulative ploys and other underlying causes of pathogenesis, most importantly therapies. Yet a large section of vulnerable people is ignorant of these innocuous-looking immune irritants, prevailing around them, and continues to suffer. This review aims to expedite this field by a concise, informative account of seminal findings in the past few years, with particular emphasis on leading frontiers like genome-wide association studies (GWAS), epitope mapping, metabolomics etc. Drawbacks linked to current approaches and solutions to overcome them have been proposed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Allergologia et Immunopathologia - Volume 44, Issue 6, November–December 2016, Pages 580-593
نویسندگان
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