کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8844727 | 1617056 | 2018 | 22 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Prevalence and correlates of beta human papillomavirus detection in fingernail samples from mid-adult women
ترجمه فارسی عنوان
شیوع و همبستگی تشخیص ویروس پاپیلومای بتا در نمونه های ناخن از زنان متولد شده
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ویروس شناسی
چکیده انگلیسی
Cutaneous human papillomaviruses (HPVs) have not been evaluated in fingernails from healthy individuals. To determine prevalence and correlates of β-HPVs in fingernails from healthy mid-adult women, we tested archived samples collected from 2011 to 2012 using a multiplex PCR combined with Luminex technology for 46 β-HPV genotypes. One hundred thirteen (61.1%) of 185 fingernail samples were positive for β-HPV, and the median number of types detected in positive samples was 2 (interquartile range: 1-4). The most common genotypes detected were HPV-23 (βâ2) (13.5%), HPV-38 (βâ2) (13.0%), HPV-5 (βâ1) (9.2%), HPV-107 (βâ2) (8.7%), and HPV-120 (βâ2) (8.7%). In multivariate analysis, β-HPV detection was associated with age (prevalence ratio [PR] for women 40-51 years versus 30-39 years = 1.30, 95% CI: 1.05-1.62) and race (PR for non-white versus white race = 0.65, 95% CI: 0.45-0.94). The prevalence of β-HPV in fingernail samples from healthy mid-adult women was similar to the prevalence of β-HPV reported at other cutaneous sites in prior studies. We did not identify any significant health or sexual behavior predictors of β-HPV detection in fingernails. Our results support the hypothesis that fingers may serve as a source of transmission or autoinoculation of cutaneous HPVs to other anatomic sites.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Papillomavirus Research - Volume 5, June 2018, Pages 1-5
Journal: Papillomavirus Research - Volume 5, June 2018, Pages 1-5
نویسندگان
Rachel L. Winer, Tarik Gheit, Stephen Cherne, John Lin, Joshua E. Stern, Mario Poljak, Qinghua Feng, Massimo Tommasino,