Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2Â g starting dose following third molar surgery

The analgesic efficacy of a 2 g starting dose of IV paracetamol was superior over the recommended dose of 1 g in terms of magnitude and duration of analgesic effect for postoperative pain following third molar surgery, with no significant difference between groups regarding safety.