High-concentration capsaicin for the treatment of post-herpetic neuralgia and other types of peripheral neuropathic pain

An integrated analysis further demonstrated the efficacy of the high-concentration capsaicin patch and confirmed its good safety and tolerability profile. Sensory testing showed little or no effect on light brush, pinprick or warmth sensations following treatment and a slight improvement in vibration sensation. An open-label study that administered repeated applications of the high-concentration capsaicin patch over 1 year demonstrated its long-term safety with no increased incidence or severity of adverse events and no impact on neurologic function. The high-concentration capsaicin patch was well tolerated and the most common adverse events were application site-related, mild to moderate, and transient.