کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9278088 | 1222830 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Staphylococcus aureus nasal carriage is not associated with known polymorphism in the Vitamin D receptor gene
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Staphylococcus aureus nasal carriage is not associated with known polymorphism in the Vitamin D receptor gene Staphylococcus aureus nasal carriage is not associated with known polymorphism in the Vitamin D receptor gene](/preview/png/9278088.png)
چکیده انگلیسی
The vitamin D endocrine system has been shown to influence the immune response and polymorphisms in the vitamin D receptor (VDR) gene have been associated with susceptibility to infectious diseases. We determined if the Cdx2, FokI and BsmI-ApaI-TaqI polymorphisms in the VDR gene were associated with nasal carriage of Staphylococcal aureus. We defined the S. aureus nasal carriage status (persistent, intermittent or non-carriage) for a group of more that 2000 elderly volunteers. The prevalence of persistent S. aureus nasal carriage was 18%, which was, however, not associated with any of the variant VDR genotypes. Our study into genetic determinants of S. aureus carriage patterns is the largest in the field, but still we found no association between VDR gene variation and S. aureus nasal carriage.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEMS Immunology and Medical Microbiology - Volume 43, Issue 2, 1 February 2005, Pages 173-176
Journal: FEMS Immunology and Medical Microbiology - Volume 43, Issue 2, 1 February 2005, Pages 173-176
نویسندگان
Mark Claassen, Jan Nouwen, Yue Fang, Alewijn Ott, Henri Verbrugh, Albert Hofman, Alex van Belkum, André Uitterlinden,