Contrast-enhanced Ultrasound Imaging: State of the Art

The introduction of a variety of ultrasound contrast agents has a significant impact on the utilization of diagnostic ultrasound in many clinical settings. This article is intended to provide an overview of the principles behind ultrasound contrast agents along with contrast-specific imaging techniques and a review of their current and potential clinical applications. Ultrasound contrast agents have dramatically improved the sensitivity and specificity of current ultrasound diagnoses and have the potential of expanding the already broad range of ultrasound applications. Future improvements in imaging techniques combined with new developments of contrast agents will make ultrasound an even more powerful diagnostic modality.