کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
946373 | 926192 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Deep Brain Stimulation in Tourette's Syndrome
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Deep Brain Stimulation in Tourette's Syndrome Deep Brain Stimulation in Tourette's Syndrome](/preview/png/946373.png)
چکیده انگلیسی
Tourette's Syndrome (TS) is a neuropsychiatric disorder characterized by motor and vocal tics, often associated with behavioral disorders. Symptoms often disappear before or during adulthood. The pathophysiology of TS is still a matter of considerable debate. Current knowledge of cortico-basal ganglia-thalamocortical circuits provide explanations for the beneficial effects of deep brain stimulation (DBS) on tics. When conservative treatment fails in patients with severe TS, DBS may be a therapeutic option. In 1999, thalamic DBS was introduced for intractable TS. Since then, multiple targets have been used in a small number of patients, including the globus pallidus pars interna and the nucleus accumbens. Inclusion and exclusion criteria have been formulated to identify good candidates for DBS.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurotherapeutics - Volume 5, Issue 2, April 2008, Pages 339-344
Journal: Neurotherapeutics - Volume 5, Issue 2, April 2008, Pages 339-344
نویسندگان
Linda Ackermans, Yasin Temel, Veerle Visser-Vandewalle,