کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9616756 48920 2005 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Deprotection of peracetylated methyl d-ribosides through enzymatic alcoholysis: Different recognition of the anomers
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
پیش نمایش صفحه اول مقاله
Deprotection of peracetylated methyl d-ribosides through enzymatic alcoholysis: Different recognition of the anomers
چکیده انگلیسی
The anomers methyl 2,3,5-tri-O-acetyl-α-d-ribofuranoside and methyl 2,3,5-tri-O-acetyl-β-d-ribofuranoside showed a different behaviour in the Candida antarctica B lipase-catalysed alcoholysis. While the enzymatic deprotection of the former proceeded regioselectively affording methyl 2,3-di-O-acetyl-α-d-ribofuranoside in 81% yield in 3 h at 45 °C showing no further transformation, the alcoholysis of the β-diasteromer was less selective. For this anomer, mixtures of partially acetylated products were formed, but contrasting to the α epimer, full deacetylated methyl β-d-ribofuranoside was quantitatively formed at long reaction times (5 days).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Catalysis B: Enzymatic - Volume 35, Issues 1–3, 1 August 2005, Pages 70-73
نویسندگان
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