کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9670635 | 1450404 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A disposable capillary electrophoresis microchip with an indium tin oxide decoupler/amperometric detector
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
سخت افزارها و معماری
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We have fabricated a capillary electrophoresis (CE) chip-based electrochemical detection (ECD) system for measurements of the dopamine, catechol, DNA ladder, and hydrogen peroxide, respectively. The microfabricated CE-ECD systems are adequate for a disposable type and the characteristics are optimized for application in electrochemical detection. The system was realized by means of a polydimethylsiloxane-glass chip and an indium tin oxide electrode. The CE-ECD system has been fabricated with relatively simple and inexpensive methods. A capillary electrophoresis and a three-electrode electrochemical detector were fabricated on the same chip. The decoupler could mostly decouple the electrochemical detection circuit from the interference of a separation electric field. Measuring dopamine, catechol, DNA ladder, and hydrogen peroxide, respectively, was successful with a microchip. All oxidizable species could be detected in less 150Â s. Disposable CE-chips make it possible to avoid polishing and reconditioning, which are required with gold CE-chips.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microelectronic Engineering - Volumes 78â79, March 2005, Pages 563-570
Journal: Microelectronic Engineering - Volumes 78â79, March 2005, Pages 563-570
نویسندگان
Ju-Ho Kim, C.J. Kang, D. Jeon, Yong-Sang Kim,