A review of calcitonin and its use in the treatment of acute pain

A meta-analysis concluded that calcitonin was effective in the treatment of complex regional pain syndrome and systematic reviews reported benefit in the treatment of acute vertebral fracture pain. A randomized controlled trial (RCT) showed calcitonin was effective in the treatment of acute phantom limb pain, however a Cochrane review did not support its use in the treatment of metastatic bone pain although individual RCTs suggested benefit.