کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9770100 | 1501939 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Raman, IR and thermal study of a new highly biocompatible phosphorylcholine-based contact lens
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
In this study, vibrational Raman and IR spectroscopy coupled to thermogravimetry (TG) and differential scanning calorimetry (DSC) have been used to characterize the Proclear⢠lens, a biomimetic soft contact lens composed of Omafilcon A, a phosphorylcholine (PC)-modified poly(2-hydroxyethyl-methacrylate) (PHEMA), whose main monomer is 2-methacryloyloxy-ethylphosphorylcholine. Raman and IR spectra showed that the PC component is actually incorporated into the polymer. The νOH Raman stretching region demonstrated that the Proclear⢠lens contains a higher amount of water (59% by TG analysis) than commercial PHEMA lenses, confirming that the PC incorporation has noticeably altered the material properties. DSC comparative analysis was carried out on Proclear⢠and PHEMA lenses as well as Acuvue⢠(Etafilcon A), a commonly used soft contact lens with a water content comparable to that of Proclearâ¢. The latter revealed to be characterized by a significantly higher free water fraction than PHEMA; this result explains why the former lens absorbs few tear components than the latter. Conversely, free water fraction was found to be nearly the same for Proclear⢠and Acuvue⢠lenses; the noticeably lower protein adsorption reported for the former was explained, partially at least, in relation to the different organization of water molecules in the two lenses.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volumes 744â747, 3 June 2005, Pages 507-514
Journal: Journal of Molecular Structure - Volumes 744â747, 3 June 2005, Pages 507-514
نویسندگان
Paola Taddei, Federica Balducci, Rosa Simoni, Patrizia Monti,