کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9954786 | 1557935 | 2018 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Postmenopausal osteoporosis and breast cancer: The biochemical links and beneficial effects of functional foods
ترجمه فارسی عنوان
پوکی استخوان پس از یائسگی و سرطان پستان: پیوندهای بیوشیمیایی و اثرات مفید غذاهای عملکردی
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
BRCABmp6BIN1CpGAPCTP53DMBAPVT1Ataxia-telangiectasiaHox transcript antisense intergenic RNARANKLPlasmacytoma variant translocation 1HER2BDNF-ASTNFSF11UCA1GSTP1Sp-1 - SP-1adenomatous polyposis coli - آدنوماتوز پولیپوزیس کولی یا آدنوماتوس پولیپوزیس کولای Effects - اثراتATM - خودپردازmetastasis associated lung adenocarcinoma transcript 1 - رونوشت آدنوکارسینوم ریه متاستاز 1Breast cancer - سرطان پستانFunctional foods - غذای فراسودمندphosphatase and tensin homolog - فسفاتاز و تنسین همولوگLinks - لینک هاMALAT1 - مالتا 1HOTAIR - هوای گرمtumor protein 53 - پروتئین تومور 53activator protein-1 - پروتئین فعال کننده-1Bone morphogenetic protein 6 - پروتئین مورفوژنیک استخوان 6postmenopausal - پس از یائسگیbridging integrator 1 - پل مونتاژ 1Osteoporosis - پوکی استخوانPten - ژن PTENEstrogen receptor - گیرنده استروژنHuman epidermal growth factor receptor 2 - گیرنده عامل فاکتور رشد اپیدرمی انسان 2Progesterone receptor - گیرنده پروژسترون
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
چکیده انگلیسی
Breast cancer as a multifactorial disease has been classified among the major causes of morbidity and mortality in women across the world, with a higher prevalence among post-menopausal women. Osteoporosis, a condition characterized by altered bone mineralization is also commonly found among post-menopausal women. Consequently, post-menopausal women are at risk of morbidity and mortality associated with breast cancer and postmenopausal osteoporosis. This may not be unconnected to the fact that, there may be existent biochemical links between the two mayhems, which might rally round between the cellular and molecular connectivity based on the actions and inactions of RANKL, estrogen, free radicals-induced oxidative stress and metabolic implications of age related obesity among others. Cells and tissues including breast and bone are more prone to oxidative stress with age, and oxidative stress could alter the activity of key proteins and pathways required for protection against breast cancer and osteoporosis. As a result, the potentials of antioxidant rich functional foods in preventing, managing and possibly treating breast cancer and postmenopausal osteoporosis cannot be overemphasised. This review mainly uses ISI, SCOPUS and PubMed indexed journals and books containing various experimental reports vacillating from humans, animals and in vitro studies in relation to breast cancer and postmenopausal osteoporosis, biochemical links and possible beneficial effects of functional foods. One distinct feature of the review is that it categorically intends to provide a critical appraisal on the said available experimental data within the variables of breast cancer and osteoporosis among females vis-Ã -vis the potentials of functional foods.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 107, November 2018, Pages 571-582
Journal: Biomedicine & Pharmacotherapy - Volume 107, November 2018, Pages 571-582
نویسندگان
Aliyu Muhammad, Sanusi Bello Mada, Ibrahim Malami, Gilead E. Forcados, Ochuko L. Erukainure, Hadiza Sani, Ibrahim Babangida Abubakar,