Keywords: AKR; aldo-keto reductase; AOX1; aldehyde oxidase 1; 11β-HSD; 11β-hydroxysteroid dehydrogenase; CBR; carbonyl reductase; CYP; cytochrome P450; EDTA; ethylenediamine-N,N,N',N'-tetraacetic acid; G-6-P; glucose-6-phosphate; G-6-PDH; glucose-6-phosphate
مقالات ISI (ترجمه نشده)
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Keywords: 11βHSD; 11β-Hydroxysteroid dehydrogenase; ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; BCRP; breast cancer resistance protein; CAR; constitutive androstane receptor; CYP; cytochrome P45
Keywords: 11β-HSD; 11β-hydroxysteroid dehydrogenase; ACTH; adrenocorticotropic hormone; AVP; arginine vasopressin; BNST; bed nucleus of the stria terminalis; BPA; bisphenol A; CBG; corticosteroid-binding globulin; CORT; corticosterone; CRF; Corticotropin-Releasin
Keywords: 11BHSD; 11β-hydroxysteroid dehydrogenase; ACTH; adrenocorticotropic hormone; AE; adverse event; ALT; alanine aminotransferase; AUC; area under the curve; BMI; body mass index; CBG; cortisol binding globulin; CL/F; apparent total clearance of the drug fro
Keywords: Steroid receptor genes; Steroid conversion; Transplantation; Kidney; Tolerance; Chronic rejection; 11β-HSD; 11β-Hydroxysteroid dehydrogenase; C1s; Complement component 1, s subcomponent gene; CISH; Cytokine inducible SH2-containing protein gene; CNI; ca
Keywords: Intraindividual stability; Cortisol; Cortisone; The ratio of cortisol to cortisone; 11β-Hydroxysteroid dehydrogenase; Tandem mass spectrometry;
Keywords: human milk; steroids; infant; newborn; gut microbiota; gastrointestinal microbiome; HPA axis; hypothalamus-pituitary-adrenal axis; 11β-HSD; 11β-hydroxysteroid dehydrogenase; ACTH; adrenocorticotropin hormone; CRH; corticotropin releasing hormone; LC
Keywords: Apoptosis; Bone marrow; Bursa of Fabricius; Corticosterone; Cortisol; Glucocorticoid receptor; Immunosteroid; Stress; Thymus; 11β-Hydroxysteroid dehydrogenase;
Keywords: 11-DHC; 11-dehydrocorticosterone; 11β-HSD1; 11β-hydroxysteroid dehydrogenase; 4; -(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES); CBG; Corticosteroid binding globulin; H6PD; Hexose-6-phosphate dehydrogenase; SDR; Steroid displacement reagent;
Keywords: ACTH; adrenocorticotropic hormone; AFC; alveolar fluid clearance; ALI; acute lung injury; ARDS; acute respiratory distress syndrome; 11β-HSD; 11β-hydroxysteroid dehydrogenase; 11β-HSD1; 11β-hydroxysteroid dehydrogenase type 1; 11β-HSD2; 11β-hydroxys
Keywords: primary aldosteronism; 11β-hydroxysteroid dehydrogenase; apparent mineralocorticoid excess; epithelial sodium channel; congenital adrenal hyperplasia; familial hyperkalemic hypertension; mineralocorticoid receptor;
Keywords: 11β-HSD; 11β-hydroxysteroid dehydrogenase; 17β-HSD; 17β-hydroxysteroid dehydrogenase; ACAT; acyl-CoA:cholesterol acyltransferase; DTT; dithiothreitol; DMEM; Dulbecco's modified Eagle's medium; ÎR; endoplasmic reticulum; GFP; green-fluorescent protein
Keywords: 21-Hydroxylase deficiency; Congenital adrenal hyperplasia; Cortisol metabolism; 11β-Hydroxysteroid dehydrogenase;
Keywords: ACTH; adrenocorticotropic hormone; AR; androgen receptor; 5α-DH-DOC; 5α-dihydro-deoxycorticosterone; CRH; corticotropin-releasing hormone; DOC; deoxycorticosterone; GC; glucocorticoid; GD; gestation day; GR; glucocorticoid receptor; 3β-HSD; 3β-hydroxy
Thiazolo[3,2-a]pyrimidin-5-one derivatives as a novel class of 11β-hydroxysteroid dehydrogenase inhibitors
Keywords: Thiazolo[3,2-a]pyrimidine derivatives; 11β-Hydroxysteroid dehydrogenase; Enzyme inhibitors; Molecular docking;
A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1
Keywords: Thiazolone derivatives; 11β-Hydroxysteroid dehydrogenase; Enzyme inhibitors; Synthesis; Molecular docking;
11β-hydroxysteroid dehydrogenase-1 deficiency alters brain energy metabolism in acute systemic inflammation
Keywords: 3PGA; 3-phosphoglyceraldehyde; 11β-HSD1; 11β-hydroxysteroid dehydrogenase type-1; 11-DHC; 11-dehydrocorticosterone; DHAP; dihydroxyacetone phosphate; HPA; hypothalamicpituitary-adrenal; LPS; lipopolysaccharide; OAA; oxaloacetic acid; TCA; tricarboxylic
Microbiota affects the expression of genes involved in HPA axis regulation and local metabolism of glucocorticoids in chronic psychosocial stress
Keywords: Chronic psychosocial stress; Mice; Microbiome; Colon; Adrenal gland; Immune system; CRH system; Cytokines; Local metabolism of glucocorticoids; 11β-hydroxysteroid dehydrogenase;
Endocrine disruptors and other inhibitors of 11β-hydroxysteroid dehydrogenase 1 and 2: Tissue-specific consequences of enzyme inhibition
Keywords: 11β-hydroxysteroid dehydrogenase; Inhibitor; Endocrine disruptor; Testis; Colon; Adipose tissue; Brain; Placenta;
Transcriptomic profiling of male European eel (Anguilla anguilla) livers at sexual maturity
Keywords: ACAT1; acetyl-coenzyme A acetyltransferase 1-like; ACP; acyl carrier protein; ABC; ATP-binding cassette; ABCA1; ATP-binding cassette sub-family A member 1; ABCD3; ATP-binding cassette sub-family D member 3; DAGT1; diacylglycerol O-acyltransferase 1-like;
A review on the effects of PBDEs on thyroid and reproduction systems in fish
Keywords: PBDEs; polybrominated diphenyl ethers; HPT; hypothalamic-pituitary-thyroid; THs; thyroid hormones; TRs; thyroid receptors; BFRs; brominated flame retardants; cyp19a; cytochrome P450 aromatase A; 11β-hsd; 11β-hydroxysteroid dehydrogenase; PCBs; polyc
Further cycloartane and friedelane triterpenoids from the leaves of Caloncoba glauca
Keywords: Caloncoba glauca; Cycloartane; Friedelane; 11β-Hydroxysteroid dehydrogenase;
Multi-matrix assay of cortisol, cortisone and corticosterone using a combined MEPS-HPLC procedure
Keywords: CRL; cortisol; CRN; cortisone; CRS; corticosterone; HPA; hypothalamic-pituitary-adrenal; 11β-HSD; 11β-hydroxysteroid dehydrogenase; DBS; dried blood spots; DUS; dried urine spots; IA; immunoassay; MEPS; microextraction by packed sorbent; FHA; former her
Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism
Keywords: 11β-hydroxysteroid dehydrogenase; Glucocorticoid; Adipocyte; Lipolysis; Metabolic syndrome; Fructose; Metabolism; 11β-HSD; 11β-hydroxysteroid dehydrogensae; ATGL; adipocyte triglyceride lipase; C/EBPα; CCAT/enhancer-binding protein α; DMEM; Dulbeccoâ
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone
Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d
FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance
Keywords: 11β-HSD; 11β-hydroxysteroid dehydrogenase; BSA; Bovine serum albumin; CNR1; Cannabinoid receptor 1; FBS; Fetal bovine serum; FKBP5; FK506-binding protein 5; FKBP51; 51 kDa FK506-binding protein 5; GEO; Gene Expression Omnibus; GR; Glucocorticoid recept
Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11β-hydroxysteroid dehydrogenase 1 inhibitors
Keywords: 11β-Hydroxysteroid dehydrogenase; 2-Benzazolylpiperazine; Structure-activity relationships (SAR); Metabolic diseases; Molecular modeling;
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Strategies to eliminate reactive metabolites
Keywords: 11β-Hydroxysteroid dehydrogenase; 11β-HSD; PF-915275; Reactive metabolite; Bioactivation; Glutathione adduct; Diabetes; Inhibitor;
Characteristics of novel hair-based biomarker for the activity assessment of 11β-hydroxysteroid dehydrogenase
Keywords: Hair cortisol; Hair cortisone; The ratio of cortisol to cortisone; 11β-hydroxysteroid dehydrogenase; Tandem mass spectrometry;
7α-Hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in EtC cerebellar neurons
Keywords: DHEA; 3β-hydroxy-5-androstene-17-one (dehydroepiandrosterone); 7OH-DHEA; 7-hydroxy-dehydroepiandrosterone; 11β-HSD1 or 2; 11β-hydroxysteroid dehydrogenase isoform 1 or 2; H6PDH; hexose-6-phosphate dehydrogenase; CORT; corticosterone; 11-dehydro-CORT; 1
Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1
Keywords: Triadimefon; 11β-Hydroxysteroid dehydrogenase; Metabolism; Liver microsomes; Azole fungicide; Molecular docking;
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione
Keywords: 11KA4; 11-ketoandrostenedione; 11KT; 11-ketotestosterone; 11OH-5α-dione; 11β-hydroxy 5α-androstanedione; 11OH-AST; 11β-hydroxyandrosterone; 11OHA4; 11β-hydroxyandrostenedione; 11OHT; 11β-hydroxytestosterone; 11βHSD; 11β-hydroxysteroid dehydrogenas
Inhibition of human and rat 11β-hydroxysteroid dehydrogenases activities by bisphenol A
Keywords: 11β-Hydroxysteroid dehydrogenase; 11β-HSD1; 11β-HSD2; Glucocorticoid metabolism;
Localization and functional activity of cytochrome P450 side chain cleavage enzyme (CYP11A1) in the adult rat kidney
Keywords: CYP11A1; cytochrome P450 side chain cleavage enzyme; CYP17; cytochrome P450 17α-hydroxylase/17,20 lyase/17,20 desmolase; GAPDH; glyceraldehyde phosphate dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase; 11β-HSD; 11β-hydroxysteroid dehydrogenase
Liquorice and glycyrrhetinic acid increase DHEA and deoxycorticosterone levels in vivo and in vitro by inhibiting adrenal SULT2A1 activity
Keywords: 11HSD; 11β-hydroxysteroid dehydrogenase; DOC; deoxycorticosterone; DHEA; dehydroepiandrosterone; ELISA; enzyme linked immunosorbant assay; GA; glycyrrhetinic acid; SULT2A1; hydroxysteroid sulfotransferase 2A1; RAAS; renin-angiotensin-aldosterone syst
Aldosterone-Induced Fibrosis in the Kidney: Questions and Controversies
Keywords: Aldosterone; kidney; inflammation; fibrosis; mineralocorticoid receptor; 11-dehydrocorticosterone; 11β-hydroxysteroid dehydrogenase;
The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
Keywords: Glucocorticoid; Inflammation; 11β-Hydroxysteroid dehydrogenase;
Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors
Keywords: 11β-Hydroxysteroid dehydrogenase; 11β-HSD1; 11β-HSD2; Selective inhibitor; Hydroxamic acid; Glycyrrhizin; Glycyrrhetinic acid; Carbenoxolone; Glucocorticoid metabolism; Cortisone metabolism; Inflammation; Chronic inflammatory disease; Cancer;
Review11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress
Keywords: 11β-Hydroxysteroid dehydrogenase; Glucocorticoids; Mineralocorticoids; HPA axis; Ageing; Anxiety; Developmental programming;
Research ArticleBile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice
Keywords: HPA; hypothalamic-pituitary-adrenal; ACTH; adrenocorticotropic hormone; 3αHSD; 3α-hydroxysteroid dehydrogenase; FXR; farnesoid X receptor; Cyp7a1; cholesterol 7α-hydroxylase; 11βHSD; 11β-hydroxysteroid dehydrogenase; BDL; bile duct ligation; THB;
ReviewGlucocorticoids, osteocytes, and skeletal fragility: The role of bone vascularity
Keywords: Glucocorticoid-induced osteoporosis; Fractures; Osteoblast and osteocyte apoptosis; Bone formation; 11β-hydroxysteroid dehydrogenase; Bone vasculature; Bone hydration; Angiogenesis; Bone density; Bone strength; Osteonecrosis;
11β-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds
Keywords: 11β-Hydroxysteroid dehydrogenase; Glucocorticoid metabolism; Metabolic syndrome; Obesity; Diabetes;
The (+)- and (â)-gossypols potently inhibit human and rat 11β-hydroxysteroid dehydrogenase type 2
Keywords: Steroids; Gossypol; 11β-Hydroxysteroid dehydrogenase;
The urinary steroid profile in patients diagnosed with adrenal incidentaloma
Keywords: Adrenal incidentaloma; Urinary steroids; Gas chromatography; 11β-hydroxysteroid dehydrogenase; 5β-reductase; Tetrahydrocortisol;
A novel NADP+-dependent dehydrogenase activity for 7α/β- and 11β-hydroxysteroids in human liver nuclei: A third 11β-hydroxysteroid dehydrogenase
Keywords: Corticosterone; Dehydrocorticosterone; Dehydroepiandrosterone; DHEA; 7α-hydroxy-DHEA; 7β-hydroxy-DHEA; 7-oxo-DHEA; 11β-hydroxysteroid dehydrogenase; Liver; Human;
Expression and activities of 11βHSD enzymes in the testes and reproductive tracts of sexually immature male pigs
Keywords: 11β-Hydroxysteroid dehydrogenase; Testis; Reproductive tract; Pig; Pre-pubertal;
Hypokalemia During Sickle Cell Crises Apparently Due to Intermittent Mineralocorticoid Excess
Keywords: Apparent mineralocorticoid excess syndrome; 11β-hydroxysteroid dehydrogenase; hypokalemia; transtubular potassium gradient (TTKG); fractional excretion of potassium (FEK); bilirubin; bile acids; sickle cell disease;
ReviewRapid mechanisms of glucocorticoid signaling in the Leydig cell
Keywords: Rapid action; Glucocorticoids; Leydig cell; 11β-Hydroxysteroid dehydrogenase;
Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11β-hydroxysteroid dehydrogenase type 1) gene
Keywords: Glucocorticoid; 11β-Hydroxysteroid dehydrogenase; Cushing syndrome; Metabolic syndrome; Cytokine;
Alteration of the cortisol-cortisone shuttle in leprosy type 1 reactions in leprosy patients in Hyderabad, India
Keywords: 11β-Hydroxysteroid dehydrogenase; Prednisolone; Cytokine; Leprosy;