دانلود مقالات ISI درباره 5Hmc + ترجمه فارسی

اپی ژنتیک در لوسمی لنفوبلاستی حاد کودکان

Epigenetics in pediatric acute lymphoblastic leukemia

Keywords: 5mc; 5-methyl cytosine; 5hmc; 5-hydroxymethylcytosine; ALL; Acute Lymphoblastic Leukemia; ASE; Allele-specific gene expression; B-All; B-cell precursor lineage ALL; CpG; CG dinucleotide; CGI; CpG island; CIMP; CpG island methylator phenotype; DMCs; Differ

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

اپی ژنتیک و تومورهای سلول ژنتیکی بیضه

Epigenetics and testicular germ cell tumors

Keywords: TGCTs; testicular germ cell tumors; GCNIS; germ cell neoplasia in situ; ESCs; embryonic stem cells; ECCs; embryonal carcinoma cells; PGCs; primordial germ cells; IGCNU; Intratubular germ cell neoplasia of the unclassified type; CIS; Carcinoma in Situ; hPG

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

بررسی 5-متیل سیتوزین و 5-هیدروکسی متیل سیتوزین به عنوان بیومارکرهای بالقوه برای مشخص کردن حساسیت های شیمیایی

Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens

Keywords: 5hmC; 5-Hydroxymethylcytosine; 5mC; 5-Methylcytosine; AOO; Acetone:olive oil; DMR; Differentially methylated region; DNCB; 2,4-Dinitrochlorobenzene; hMmeDIP; Hydroxymethylated DNA immunoprecipation; IFN; Interferon; IL; Interleukin; IP; Immunoprecipitated

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

انتقال ترانس ژنراتور فعال سازی سلول های مضر سیستمیک-ژنتیک و ویژگی های اپی ژنتیکی

Transgenerational transmission of systemic mast cell activation disease-genetic and epigenetic features

Keywords: MCAD; mast cell activation disease; MCAS; primary mast cell activation syndrome; SM; systemic mastocytosis; miRNA; microRNA; pts; patients; CFS; chronic fatigue syndrome; MITF; microphthalmia-associated transcription factor; mC; 5'-methylcytosine; 5hmC; 5

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

دینامیک اپی ژنتیکی در ایمنی و خود ایمنی

Epigenetic dynamics in immunity and autoimmunity

Keywords: Epigenetic dynamics; Immune system; Autoimmune diseases; DNA methylation; Histone modifications; DNMT; DNA methyltransferase; TET; ten-eleven translocation; AID/AICDA; activation-induced cytidine deaminase; APOBEC; Apolipoprotein B mRNA editing enzyme; BE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

تنظیم اپیژنتیک کروماتین باز در سلول های بنیادی پلورپوفنت

Epigenetic regulation of open chromatin in pluripotent stem cells

Keywords: 5hmc; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; ATP; adenosine triphosphate; BAF; Brg/Brahma-associated factor; DHS; DNase I hypersensitivity site; ESC; embryonic stem cell; GFP; green fluorescent protein; LOCK; large, organized chromatin K9 modific

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

مقررات اپیگنتیک بلوغ زن

Epigenetic regulation of female puberty

Keywords: GnRH neurons; Kisspeptin neurons; Female puberty; Chromatin modifications; DNA methylation; Transcriptional repression; Transcriptional activation; Epigenetic regulators; microRNAs; Long noncoding RNAs; 5hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosin

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

برنامه ریزی اپی ژنتیک انسفالوپاتی هیپوکسیک-ایسکمیک در پاسخ به هیپوکسی جنین

Epigenetic programming of hypoxic-ischemic encephalopathy in response to fetal hypoxia

Keywords: AID/APOBEC; activation-induced cytidine deaminase/apolipoprotein B mRNA-editing enzyme complex; BDNF; brain-derived neurotrophic factor; 5caC; 5-carboxylcytosine; CBP; CREB binding protein; CREB; cAMP response binding protein; DNMT; DNA methyltransferases

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

مقررات اپی ژنتیک در بدخیمی های میلوئیدی

Epigenetic deregulation in myeloid malignancies

Keywords: α-KG; alpha-ketoglutarate; 2-HG; 2-hydroxyglutarate; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AML; acute myeloid leukemia; ASXL1; additional sex combs-like 1; AZA; azacytidine; CMML; chronic myelomonocytic leukemia; DAC; decitabine; DNMT3A;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

پروفایل های اپیگنتیک به عنوان معیارهای تعیین شده در معرض زانوبیوتیک تعریف شده است

Epigenetic profiles as defined signatures of xenobiotic exposure

Keywords: 5caC; 5-carboxylcytosine; 5fC; 5-formylcytosine; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; CAR; constitutive androstane receptor; CGI; CpG island; CpG; cytosinephosophate-guanine; CNV; copy number variation; DEN; diethylnitrosamine; DNMT; DNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

غنی سازی محیطی دینامیک 5 هیدروکسی متیل سیتوزین را در هیپوکامپ متصل می کند

Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus

Keywords: Enriched environment; DNA methylation; 5hmC; Epigenetics; Axon guidance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

قرار گرفتن در معرض آرسنیک از طریق آب آشامیدنی باعث تغییرات 5-هیدروکسی متیل سیتوزین در موش صحرایی می شود

Exposure to arsenic via drinking water induces 5-hydroxymethylcytosine alteration in rat

Keywords: 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AS3MT; arsenite methyltransferase; DNMT; DNA methyltransferase; SAM; S-adenosylmethionine; TET; tetmethylcytosinedioxygenase; Arsenic; DNA methylation; DNA demethylation; 5-Hydroxymethylcytosine; 5-Met

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

تنظیم اپی ژنتیک ایزوفرم های گیرنده پروژسترون: از مدل های کلاسیک به مغز جنسی

Epigenetic regulation of Progesterone Receptor isoforms: From classical models to the sexual brain

Keywords: Progesterone Receptor isoforms; Epigenetic regulation; Sexual brain; 3C; chromosome conformation capture; 5hmC; 5 hydroxymethylcytosine; Ago; Argonaute; AP1; Activator Protein 1; AZA; aza-2′-deoxycytidine; ChIP; chromatin immunoprecipitation; DHSS; Dnas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Alterations of DNA methylation in parathyroid tumors

Keywords: Parathyroid tumors; Hyperparathyroidism; PTH; Methylation; Chromatin modifiers; Histones; MEN1; multiple endocrine neoplasia type 1; HPT-JT; hyperparathyroidism- jaw tumors; CpG; cytosine phosphate guanine; 5hmc; 5-hydroxymethylcytosine; TET1; tet (ten-el

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Selective inhibition of CTCF binding by iAs directs TET-mediated reprogramming of 5-hydroxymethylation patterns in iAs-transformed cells

Keywords: 5mC; 5-methylCytosine; 5hmC; 5-hydroxymethylCytosine; EMT; epithelial-to-mesenchymal transition; iAs; inorganic arsenic; iAs-T; inorganic arsenic transformed cells; NT; non-treated cell; qRT-PCR; quantitative reverse transcription-PCR; ChIP-qRT-PCR; chrom

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Vitamin C - A new player in regulation of the cancer epigenome

Keywords: 5caC; 5-carboxylcytosine; 5fC; 5-formylcytosine; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AML; acute myeloid leukemia; DHA; dehydroascorbic acid; DNMT; DNA methyltransferase; DNMTis; DNA methyltransferase inhibitors; GLUT; glucose transporter

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases

Keywords: BER; base excision repair; 5caC; 5-carboxylcytosine; CPDB; ConsensuspathDB; DEGs; differentially expressed genes; DhMRs; differentially hydroxyl-methylated regions; DNMTs; DNA methyltransferases; 5fU; 5-formyluracil; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

Keywords: Tet2; 5hmC; Macrophage; Osteoclast; Runx1;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

The role of TET-mediated DNA hydroxymethylation in prostate cancer

Keywords: Prostate cancer; Epigenetics; TET; DNA hydroxymethylation; 5hmC;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Early pathogenesis during infectious bursal disease in susceptible chickens is associated with changes in B cell genomic methylation and loss of genome integrity

Keywords: B-cell; T-cell; CD40L; Infectious bursal disease virus (IBDV); 5-Hydroxymethylcytosine (5hmC); IBDV; Infectious Bursal Disease Virus; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; Tet; Ten-11 translocation; BF; bursa of Fabricius; RIR; Rhode Islan

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects

Keywords: 5fC; 5-formylcytosine; 5caC; 5-carboxycytosine; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; ACTB; b-actin; ASD; autism spectrum disorder; BA; Brodmann area; BDNF; brain derived neurotrophic factor; BDNF-IV; BDNF-promoter 4; BDNF-IX; BDNF-promote

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Maternal SENP7 programs meiosis architecture and embryo survival in mouse

Keywords: meiosis I/II; the first/second meiotic division; MI/MII; metaphase I/II; MPF; M-phase promoting factor; Cdk1; Cyclin-dependent kinase 1; APC; anaphase promoting complex; BrdU; bromodeoxyuridine; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectas

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina

Keywords: Dnmt1; Dnmt3a; Dnmt3b; Epigenetics; Retina; OPL; DNA methylation; 5mC; 5hmC;

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

The Ciona intestinalis cleavage clock is independent of DNA methylation

Keywords: AChE; acetylcholinesterase; TET; ten-eleven translocation; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; MS; mass spectrometry; WGBS; whole genome bisulfite sequencing; PBAT; post-bisulfite adaptor tagging; DMR; differentially methylated region; T

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Active DNA demethylation by DNA repair: Facts and uncertainties

Keywords: 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5hmU; 5-hydroxymethyluracil; 5fC; 5-formylcytosine; 5caC; 5-carboxycytosine; AID; activation-induced deaminase; APE1; apurinic/apyrimidinic endonuclease 1; APOBEC; apolipoprotein B mRNA editing enzyme,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondrial DNA copy number and replication in reprogramming and differentiation

Keywords: mtDNA; mitochondrial DNA; D-Loop; displacement loop; TFAM; mitochondrial transcription factor A; mtSSB; mitochondrial DNA single stranded binding protein; POLG; DNA polymerase gamma; OH; origin of heavy strand replication; 5mC; 5-methylcytosine; 5hmC; 5-h

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

OGG1 is essential in oxidative stress induced DNA demethylation

Keywords: OGG1; 8-Oxoguanine DNA glycosylase-1; 8-oxoG; 8-Oxoguanine; ROS; reactive oxygen species; α-KG; α-Ketoglutarate; MeDIP; methylated DNA immunoprecipitations; 5mC; 5-Methyl cytosine; 5hmC; 5-Hydroxymethyl cytosine; 5fC; 5-Formylcytosine; 5caC; 5-Carboxylc

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes

Keywords: ACTB; cytoplasmic beta actin; DNMT1, 3A, 3B; DNA methyltransferase 1, 3A, 3B; CG; cytosine-guanine dinucleotide; CNS; conserved noncoding sequence; CT; cycle threshold; GADD45A, B, G; Growth arrest DNA damage inducible proteins 45a, 45b, 45g; 5hmC; 5′-h

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2016 سفارش ترجمه

Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling

Keywords: 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; 5hmU; 5-hydroxymethyluracil; BER; base excision repair; TET; Ten-eleven translocation; TDG; thymine DNA glycosylase; βGT; β-glucosyltransferase; AID;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNAs mediated targeting on the Yin-yang dynamics of DNA methylation in disease and development

Keywords: 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formalcytosine; 5caC; 5-carboxylcytosine; DNMTs; DNA methyltransferases; TET; Ten-eleven translocation family; TDG; thymine-DNA glycosylase; PRC; polycomb repressive complex; H3K27me3; trimethyl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives

Keywords: C; Cytosine; DNMT; DNA methyl transferase; BER; Base Excision Repair; NER; Nucleotide Excision Repair; TET; Ten Eleven Translocation protein; 5mC; 5methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; ESC; Embryo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Germline-derived DNA methylation and early embryo epigenetic reprogramming: The selected survival of imprints

Keywords: 5mC; 5-methylcytosine; ES cells; embryonic stem cells; SAM; S-adenosyl-methionine; Dnmt; DNA methyltransferase; Uhrf1; Ubiquitin-like, containing PHD and RING finger domains 1; H3K; Histone H3 lysine; Cfp1; CXXC finger protein 1; Ezh2; enhancer of zeste h

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis

Keywords: ESC; embryonic stem cell; iPSC; induced pluripotent stem cell; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; FoxA2; forkhead box A2; Sox17; sex determining region Y box 17; Oct-4; octamer-binding transcription factor 4; CDH1; E-cadherin-1; IGFR; i

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells

Keywords: B cell differentiation; plasmablast; plasma cell differentiation; DNA methylation; 5hmC

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Ethanol deregulates Mecp2/MeCP2 in differentiating neural stem cells via interplay between 5-methylcytosine and 5-hydroxymethylcytosine at the Mecp2 regulatory elements

Keywords: 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; bFGF; basic fibroblast growth factor; Ct; threshold cycle values; DAPI; 4′,6-diamidino-2-phenylindole; D; day; DMEM/F12; Dulbecco's Modified Eagle Medium: Nutrient Mixture F-12; E; embryonic day; EDT

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG|GTG) increases binding of the Tcf3|Ascl1 helix-loop-helix heterodimer 10-fold

Keywords: C; cytosine; B-HLH; basic-helix-loop-helix; E-Box; Enhancer Box; Tcf3; transcription factor 3; Tcf4; transcription factor 4; Tcf12; transcription factor 12; Ascl1; Achaete-scute homolog 1; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Connections between TET proteins and aberrant DNA modification in cancer

Keywords: TET; 5-hydroxymethylcytosine; 5mC; 5hmC; DNA methylation; DNA demethylation; cancer; IDH; OGT

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a

Keywords: MicroRNA; Epigenetics; Tet; TDG; 5hmC;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

A mechanistic overview of TET-mediated 5-methylcytosine oxidation

Keywords: TET; Ten-Eleven Translocation; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; 2OG; 2-oxoglutarate; KDM; histone lysine demethylase; PHD; Prolyl-hydroxylase-domain; FIH; Factor-inhibiting-HIF; Epigene

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool

Keywords: AD; Alzheimer disease; AIMs; amplification of inter-methylated sites; ALS; amyotrophic lateral sclerosis; ChIP; chromatin immunoprecipitation; CTH; cystathionine γ-lyase; CHARM; comprehensive high-throughput arrays for relative methylation; CBS; cystathi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

ReviewEpigenetics of stress adaptations in the brain

Keywords: Epigenetics; Gene expression; Brain; Limbic system; Stress; Behavior; 5hmC; 5′-hydroxymethyl-2′-deoxycytidine; 5-HT; serotonin; CA; cornu ammonis; DG; dentate gyrus; DNMT; DNA methyltransferase; GR; glucocorticoid receptor; HPA; hypothalamic-pituita

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Genome-wide distribution of DNA methylation and DNA demethylation and related chromatin regulators in cancer

Keywords: DNA methylation; DNA demethylation; 5mC; 5hmC; DNMT; TET

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Folic Acid Increases Global DNA Methylation and Reduces Inflammation to Prevent Helicobacter-Associated Gastric Cancer in Mice

Keywords: Folate; Gastric Cancer; DNA Methylation; Cancer-Associated Fibroblasts; 5HmC; 5-hydroxy-methylcytosine; 5mC; 5-methylcytosine; FA; folic acid; IHC; immunohistochemistry; INS-GAS; transgenic hypergastrinemic; αSMA; α-smooth muscle actin; WT; wild type;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression

Keywords: 5meC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; CMVIE; cytomegalovirus immediate early promoter; 5-Hydroxymethylcytosine; 5-Methylcytosine; Epigenetics; Gene regulation; Transcription;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه