Keywords: Esophageal Cancer; Genomics; Epigenomics; ADAR; adenosine deaminases acting on RNA; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; BCH; basal cell hyperplasia; CIS; carcinoma in situ; CNA; copy number alteration; ESCC; esophagea
مقالات ISI (ترجمه نشده)
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Keywords: ACTH; adrenocorticotropic hormone; ADAM10; a disintegrin and metalloprotease 10; ADAR; adenosine deaminase acting on RNA; AP1/3; adaptor protein 1/3; BLOC1-3; biogenesis of lysosome-related organelles complex 1-3; DCT; dopachrome tautomerase; DSRAD; dou
Keywords: ADAR; adenosine deaminase, RNA-specific; AI; allelic imbalance; CEPH; Centre d'Etude du Polymorphisme Humain; eQTL; expression quantitative trait loci; MAE; monoallelic expression; SNP; single nucleotide polymorphism; Single nucleotide polymorphism (SNP);
Variable clinical phenotype in two siblings with Aicardi-Goutières syndrome type 6 and a novel mutation in the ADAR gene
Keywords: Aicardi-Goutières syndrome; ADAR gene; Type 1 interferonopathy; Infantile encephalopathy; AGS; Aicardi-Goutières syndrome; ADAR; adenosine deaminase, RNA-specific; CSF; cerebrospinal fluid; dsRNA; double-stranded RNA;
APOBEC and ADAR deaminases may cause many single nucleotide polymorphisms curated in the OMIM database
Keywords: A>>T; SNPs or mutations of A exceed SNPs or mutations of T; ADAR; Adenosine Deaminase that acts on RNA. There are two main isoformsADAR1 and ADAR2 that have similar WA targeting specificity; AID; activation induced cytidine deaminase, an APOBEC family mem
ADARs and editing: The role of A-to-I RNA modification in cancer progression
Keywords: ADAR; Adenosine deamination; RNA editing; Cancer;
Global Transcriptome Analysis of RNA Abundance Regulation by ADAR in Lung Adenocarcinoma
Keywords: RNA editing; Lung adenocarcinoma; Cancer; Post-transcriptional regulation; Bioinformatics; ADAR;
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics
Keywords: ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy
Species specific RNA A-to-I editing of mosquito RDL modulates GABA potency and influences agonistic, potentiating and antagonistic actions of ivermectin
Keywords: Electrophysiology; Fipronil; GABA receptor; Ivermectin; Mosquito; RNA editing; ADAR; adenosine deaminase that acts on RNA; GABA; γ-aminobutyric acid; nAChR; nicotinic acetylcholine receptor; RDL; resistant to dieldrin, an insect GABA receptor; TM; transm
Transposable element dysregulation in systemic lupus erythematosus and regulation by histone conformation and Hsp90
Keywords: Adar; RNaseL; Lupus; Heat shock; Epigenetics; Histone deacetylase inhibitor; 17-AAG; 17-Demethoxy-17-(2-propenylamino) geldanamycin; APOBEC; Apolipoprotein B mRNA Editing Enzyme Catalytic Polypeptide-Like; ERV; Endogenous retrovirus; H3K4me3; Histone 3, l
Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
Keywords: Enoxacin; MicroRNA; Aging; miR-34; Mitohormesis; ADAR;
Mechanism of N6-methyladenosine modification and its emerging role in cancer
Keywords: ADAR; adenosine deaminase, RNA specific; α-KG; α-ketoglutarate; ALKBH5; alkB homologue 5; AML; acute myeloid leukemia; CDS; coding sequences; CLIP; cross-linking and immunoprecipitation; eIF3; eukaryotic initiation factor 3; ESC; embryonic stem cell; FO
ADAR deaminase A-to-I editing of DNA and RNA moieties of RNA:DNA hybrids has implications for the mechanism of Ig somatic hypermutation
Keywords: A>>T; mutations of A exceed mutations of T, e.g. as found in normal murine physiological SHM in vivo by 2.9 fold; Aag; alkyladenine DNA glycosylase; ADAR; Adenosine Deaminase that acts on RNA; AID; activation induced cytidine deaminase, a APOBEC family me
In cancer, A-to-I RNA editing can be the driver, the passenger, or the mechanic
Keywords: ADAR; Chemotherapeutic drug sensitivity; Cancer biomarkers; Gene therapy;
RNA editing independently occurs at three mir-376a-1 sites and may compromise the stability of the microRNA hairpin
Keywords: A; adenosine; ADAR; adenosine deaminase; Cq; quantification cycle; dsRNA; double-stranded RNA; G; guanosine; I; inosine; MFE; minimum free energy; mRNA; messenger RNA; miRNA; microRNA; NGS; next generation sequencing; nt; nucleotide; RT-qPCR; real time qu
Evolutionary conservation and expression of miR-10a-3p in olive flounder and rock bream
Keywords: miRNAs; MicroRNAs; ncRNAs; non-coding RNAs; 3â² UTR; 3â² untranslated region; VHSV; viral hemorrhagic septicemia virus; GO; gene ontology; ssRNAs; single-stranded RNAs; Hox; homeobox; GCSF; granulocyte colony stimulating factor; S. parauberis; Streptoco
Synthesis of native-like crosslinked duplex RNA and study of its properties
Keywords: RNA; Crosslinking reaction; 6-Vinylpurine; ADAR; Native-like;
Single-Strand Consensus Sequencing Reveals that HIV Type but not Subtype Significantly Impacts Viral Mutation Frequencies and Spectra
Keywords: HIV-1; human immunodeficiency virus type-1; m/bp; mutations/base pair; RT; reverse transcriptase; ADAR; adenosine deaminase acting on RNA; HIV-2; human immunodeficiency virus type-2; SSCS; single-strand consensus sequencing; MOI; multiplicity of infection
The mysterious circle: Molecular curiosities of RNA mediated gene regulation
Keywords: ADAR; adenosine deaminases acting on RNA; circRNA; circular RNA; EcircRNA; exonic circular RNA; EIcircRNA; exonic intronic circular RNA; IcircRNA; intronic circular RNA; IRES; internal ribosome entry site; ncRNA; non-coding RNA; Back splicing; Circular RN
Structural components of chemosensory protein mutations in the silkworm moth, Bombyx mori
Keywords: Insects; Lepidoptera; Cysteine; Glycine; α-helix; Protein evolution; A; adenine; ADAR; adenosine deaminase acting on RNA; APOB; apolipoprotein B; APOBEC; apolipoprotein B editing catalytic subunit; Bmor; Bombyx mori; C; cytosine; cDNA; complementary DNA;
Signaling in dopamine D2 receptor-oxytocin receptor heterocomplexes and its relevance for the anxiolytic effects of dopamine and oxytocin interactions in the amygdala of the rat
Keywords: Anxiety; Fear; Amygdala; Dopamine D2 receptor; Oxytocin receptor; Receptor-receptor interactions; Raclopride; Oxytocin; Heteroreceptor complexes; AC; adenylyl cyclase; BLA; basolateral complex; ADAR; adenosine A receptor; CAS; castor transcription factor;
RNA Editing: A Contributor to Neuronal Dynamics in the Mammalian Brain
Keywords: RNA editing; ADAR; neurotransmission
Long non-coding RNA: A newly deciphered “code” in prostate cancer
Keywords: Androgen receptor; LNCaP; Biomarker; PCa; prostate cancer; ncRNA; non-coding RNAs; lncRNA; long ncRNA; miRNA; microRNA; snRNA; small nuclear RNA; siRNA; small interfering RNA; tRNA; transfer RNA; rRNA; ribosomal RNA; PCA3; PCa antigen 3; PIN; prostatic in
ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer
Keywords: Transcriptome; Editome; RNA Editing; ADARs; ADAR; adenosine deaminase that act on RNA; A-to-G; adenosine to guanosine; A-to-I; adenosine to inosine; CDS; coding sequences; CM; catalytic mutant; DR; down-regulation; edt; edited; EV; empty vector; GC; gastr
RNA editing of non-coding RNA and its role in gene regulation
Keywords: RNA editing; ADAR; Alu repeat elements; dsRNA; circRNA;
RNA rewriting, recoding, and rewiring in human disease
Keywords: RNA editing; human disease; ADAR; degenerative disease
Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease
Keywords: RNA editing; ADAR; Glutamate; Alzheimer's disease; ApoE; Neurodegeneration; AMPA; GluA2; Postmortem; Hippocampus; Caudate; Primer extension;
The emerging role of RNA and DNA editing in cancer
Keywords: RNA editing; ADAR; APOBEC; Cancer;
HIV-1 translation and its regulation by cellular factors PKR and PACT
Keywords: ADAR; adenosine deaminase acting on RNA; ds; double-stranded; dsRBD; dsRNA binding domain; dsRBP; dsRNA binding protein; eIF; eukaryotic translation initiation factor; HCV; Hepatitis C virus; HDV; Hepatitis D virus; HIV; human immunodeficiency virus; HTLV
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone
Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d
microRNA control of interferons and interferon induced anti-viral activity
Keywords: ADAR; adenosine deaminase acting on RNA; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like; IFN; interferon; IFN-R; interferon receptor; IRF; interferon regulatory factor; JAK; janus kinase; miR or miRNA; microRNA; NO; nitric oxide;
A method to identify RNA A-to-I editing targets using I-specific cleavage and exon array analysis
Keywords: RNA editing; Inosine; Adenosine deamination; ADAR; Exon array; I-specific cleavageADAR, Adenine deaminase acting on RNA; A, adenosine; I, inosine
Zalpha-domains: At the intersection between RNA editing and innate immunity
Keywords: ADAR; adenosine deaminase acting on RNA; A to I; adenosine to inosine; PKR; protein kinase RNA depended; DAI; DNA depended Activator of IRFs; IFN; interferon; CNS; central nervous system; eIF2a; eukaryotic initiation factor 2a; HIV; human immunodeficiency
A-to-I editing of microRNAs: Regulating the regulators?
Keywords: RNA editing; microRNA; ADAR; (Endo-)siRNA; Inosine; Adenosine deamination;
The intricate relationship between RNA structure, editing, and splicing
Keywords: RNA editing; RNA structure; Transcript; Splicing; ADAR;
Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA
Keywords: RNA editing; ADAR; Drosophila; dsRBD; dsRBM; NMR; GluR-2 R/G siteADAR, adenosine deaminase that act on RNA; dADAR, Drosophila ADAR; dsRBD, double-stranded RNA binding domain; r.m.s.d, root mean square deviation
Disconnected Interacting Protein 1 binds with high affinity to pre-tRNA and ADAT
Keywords: ADAR; adenosine deaminase that acts on RNA; ADAT; adenosine deaminase that acts on tRNA; AU; analytical ultracentrifugation; DIP1; Disconnected Interacting Protein 1; DIP1-c; longest DIP1 isoform; dsRBD; double-stranded RNA-binding domain; dsRNA; double-s
Genome-wide evaluation and discovery of vertebrate A-to-I RNA editing sites
Keywords: RNA editing; ADAR; Inosine; Adenosine deamination
RNA surveillance—An emerging role for RNA regulatory networks in aging
Keywords: RNA editing; microRNA; Muscle; ADAR
Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral
Keywords: ADAR; adenosine deaminase acting on RNA; bp; base pair; dsRNA; double-stranded RNA; IFN; interferon; nt; nucleotide; PKR; protein kinase regulated by RNA; ssRNA; single-stranded RNA; UTR; untranslated region; ADAR; Double-stranded RNA; Innate immunity; In
A mammalian reporter system for fast and quantitative detection of intracellular A-to-I RNA editing levels
Keywords: RNA editing; Adar; Inosine; Adenosine deamination
Enhancing non-coding RNA information content with ADAR editing
Keywords: RNA editing; ADAR; Nervous system transcriptome; Non-coding RNA (ncRNA); ADAR activity during stress and inflammation
Characterization of ADAR1-mediated modulation of gene expression
Keywords: RNA editing; dsRNA-specific adenosine deaminase; Reporter gene expression; Inosine; ADAR; Adenosine deamination
RNA editing in regulating gene expression in the brain
Keywords: RNA editing; ADAR; RNA interference; Alu element; Ion channel; Pre-synaptic protein;
A-to-I editing challenger or ally to the microRNA process
Keywords: ADAR; RNA editing; Adenosine to inosine editing; MicroRNA; RNAi
Altered RNA editing of serotonin 2C receptor in a rat model of depression
Keywords: HTR2C; SSRI; TCA; ADAR; Psychiatric disorders; Learned helplessness;
In vivo RNA-RNA duplexes from human α3 and α5 nicotinic receptor subunit mRNAs
Keywords: bp; base pair(s); kb; kilobase(s); CHRNA3; cholinergic receptor nicotinic alpha subunit 3; CHRNA5; cholinergic receptor nicotinic alpha subunit 5; CHRNB4; cholinergic receptor nicotinic beta subunit 4; dsRNA; double-stranded RNA; nAChR; nicotinic acetylch